TY - JOUR AU - Nguyen, Tina H. AU - Alahari, Suresh K. PY - 2019 TI - Quaking as a novel target of miR-200b to regulate tumor cell cycle progression mediated angiogenesis and metastasis JF - Biotarget; Vol 3 (June 2019): Biotarget Y2 - 2019 KW - N2 - Tumor growth is mediated by several factors including metabolic function, intracellular signaling, evasion of apoptosis, tissue invasion and metastasis, and angiogenesis. Of these factors, angiogenesis is a crucial component due to its part in both delivering nutrients and providing a conduit for metastasis. Current anti-angiogenic therapies focus on tumor-derived VEGF signaling; however, these efforts are modest and prone to resistance by upregulation of other pro-angiogenic signaling (1,2). Due to incomplete knowledge of endothelial cell (EC) biology, other methods of impeding tumor angiogenesis are not available. UR - https://biotarget.amegroups.org/article/view/5038