TY - JOUR AU - Takaesu, Giichi PY - 2018 TI - Two types of TRAF6-dependent TAK1 activation in the IL-1 signaling pathway JF - Biotarget; Vol 2 (January 2018): Biotarget Y2 - 2018 KW - N2 - Interleukin-1 (IL-1) is a proinflammatory cytokine that plays a central role in the immune response during infection and chronic inflammation (1). IL-1α is constitutively expressed in the epithelial layers of the gastrointestinal tract, lung, liver, kidney, endothelial cells, and astrocytes, whereas IL-1β is mainly produced by activated macrophages and dendritic cells. UR - https://biotarget.amegroups.org/article/view/3959