@article{Biotarget3703,
author = {Rudolph M. Navari},
title = {Overview of the neurokinin-1 receptor antagonists},
journal = {Biotarget},
volume = {1},
number = {4},
year = {2017},
keywords = {},
abstract = {Neurokinin-1 (NK-1) receptor antagonists block substance P-mediated NK-1 receptors which are present in the abdominal vagus, the brainstem, and the area postrema in the brainstem. Substance P is a mammalian tachykinin that is found in vagal afferent neurons innervating the brainstem and sends impulses to the vomiting center (1). Compounds that block NK-1 receptors lessen emesis after cisplatin, ipecac, apomorphine, and radiation therapy (1).},
issn = {2522-669X}, url = {https://biotarget.amegroups.org/article/view/3703}
}