Article Abstract

Mesenchymal stem cell derived extracellular vesicles: a promising new therapeutic approach for hepatic injury

Authors: Anuradha Moirangthem, Tushar Patel

Abstract

Liver injury is a serious condition which may often lead to hepatic failure. It can occur as a consequence of insults and toxicity related to viral hepatitis, drugs, ischemia, alcohol, drugs, metabolic diseases or autoimmune disease. Liver transplantation may be required in cases of acute or fulminant liver failure beyond the capacity of the liver to repair and regenerate. While this is an effective treatment option, the scarcity of organ donors, and the medical, financial and socioeconomic factors limit its utility. New approaches to ameliorate liver injury are needed.